Indeed, chemism is beginning to gain safergrounds as a scientific explanation.
Chemical processes are thoughtto play an increasingly basic role in brain
functioning. FrancisSchmidt, head of the team in charge of the programme in
neuro-sciencein the U.S.A (1977), considers that "The brain is an
electricallycontrolled chemical
machine"15.
This statement is grounded in the progress made over the recent
years in neuro-sciences. That the brain functions only by virtue
of the classical neuronic network is no doubt an outdated
view16.
The new image is based on the attention given to information processing
through gradual electronic currents and fields interacting in
local zones made up of neurons with short axons (Golgi II) and
amacrine cells without axons. In such circuits the dendrites no
longer function as passive postsynaptic receivers (as postulated
by classical neuronic theory) but they actively transmit the information
to other neurons through dendrodendritic connections and electronic
jonctions. Acting both presynaptically and postsynaptically, one
in relation with the other, the dendrites from a vast dendrodendritic
network in which information processing is averaged by gradual
electronic currents and fields. In such dendrodendritic networks
and in cortex in general, the distances between the parts that
interact bioelectrically are small, of order of
micrometers17.
Then fairly quick reactions may be locally obtained, which shows
the role of the "local circuits (LC)" in brain functioning.
These local circuits, or modules, are themselves intricately connected,
and the classical neuronic transmissions for somewhat longer distances
are subsequently at play. These discoveries entitle us to speak
of a new age in neuro-biology. This opinion is also shared by
Professor R. R. Llinas, who insists however especially on brain
functioning in molecular terms. From Roman y Cajal, our thinking
has been aimed, if not fixed, on the idea that the smallest functional
unit of the brain is the neuron. But in the last ten years, our
understanding regarding the properties of neurons indicated the
presence of some complex functional states in subneuronic aggregates
(i.e. in the dendodendritic interaction - n.n.) It is probably
more likely to extrapolate up to the conclusion that, in a fundamental
way, the brain operates at molecular
level18.
The brain issue is therefore raised in terms
of organization and chemical-molecular work. So the question is
not about the chemical transmission of information by means of
the chemical neurotransmitters from the end of the axon to the
synaptic junction; but rather about less conventional modes of
communication and chemical processing of information. According
to L. L. Iversen, the chemical substances that might be at play
are amines, amino-acids, and possibly peptides and prostaglandines.
Additionally, many questions are related to cell membranes, which
are partially responsible for the brain "secret". Organization
in terms of cell constituents is likewise largely responsible
for brain work. Let us now turn to elementary matters, which still
have something in stock for us.
G. Palade19
observes that biological tissues contain cell populations in which
any cell can do the thing that any other cell in that system can.
However, in the case of the brain, the situation changes essentially.
Here, training differs substantially from one cell to another.
The cell population is heterogeneous and heterogeneity may be
observed down to molecular work.
Palade20
notices that the research of the nervous system is still focussed
on the cell and supra-cell level, and only slightly articulate
at the sub-cell level, where heterogeneity precludes an easier
insight. However, the current tendency, Professor Palade observes,
is to judge in terms of molecular work.
However, brain chemism does not yet mark a
definite leap to the informatter, but inasmuch as a general philosophical
idea converges to chemism we may trust that further efforts may
be illuminating in this respect. Science will no doubt have to
account some day for the transition from the bioelectrical and
biochemical activities in the brain of higher organisms to psychological
processes. No conceptual principles to account for this relation,
Francis O. Schmidt observed, have been thus far
found21.
Two aspects may be used in a tentative explanation
of the interacting activity of the brain:
- the high connectivityof the cell in the nervous system, which might
explain the higherfunctions of the brain and permit even a mathematical
treatmentof the nervous system as a
continuum22 ;and
- the continuous electric potentials of the dendrodentritic
interconnecting modules (graded electrotonic potentials), which
might be the main language of the central nervous
system23.
Like aspects are no doubt only a step towards
an explanation of the integrating activity of the brain. But on
this route towards explanation, a threshold of understanding will
somewhere come up. And this threshold will have to be somehow
exceeded. Science will come to account for the almost-integration,
rather than for integration itself, for in the latter case a new
physical ingredient will most likely be necessary.
By virtue of the ring of the material world,
the mental realm exists independently of existence in itself.
However, existence in itself is by far richer than was presupposed
by Aristotle. It embraces the energymatter, the informatter and
the substance all together. It would be erroneous to think that
the mental realm is informatter or that it develops only in the
informatter. Owing to the informatter, our mental ideas are only
somehow better materially grounded than they used to be before,
as they have both substance and informatter as a support. And
if the mental realm can cause action on the substance, then it
is most likely that it may cause actions on the informatter too.
The ring of the material world was first unlocked
by Aristotle, investigated and roughly approximated by Werner
Heisenberg, and only fragmentarily illuminated or mirrored by
all philosophers more or less clearly.
Matter in profundities and matter in
the universe are not disunited. It is precisely their unity which
ensures both the origination of a universe out of the matter and
the possible action from a universe into the profound matter.
Matter in Depths22